San Jose, CA, United States of America

David W Togami


Average Co-Inventor Count = 3.0

ph-index = 4

Forward Citations = 63(Granted Patents)


Company Filing History:


Years Active: 1998-2003

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11 patents (USPTO):Explore Patents

Title: The Innovations of David W. Togami in Polynucleotide Separations

Introduction

David W. Togami, a prominent inventor based in San Jose, CA, has made significant contributions to the field of liquid chromatography, particularly in the realm of polynucleotide separations. With a commendable portfolio of 11 patents, Togami's work has paved the way for innovative methods that enhance the efficiency of separating polynucleotide fragments.

Latest Patents

Togami's latest patent details a "System and method for performing polynucleotide separations using liquid chromatography." This innovative system incorporates components made of titanium, stainless steel, or organic polymeric material, which are critical in effectively separating polynucleotide fragments, especially large double-stranded fragments. A key feature of this system is that the materials used are treated to prevent the release of multivalent cations into the aqueous solutions passing through the chromatography system. Additionally, the patent describes the use of a multivalent cation capture resin placed upstream of the separation column, designed to eliminate multivalent ions from the system. This resin can be housed in various configurations, including guard disks, guard columns, or guard cartridges. By using these novel methods, Togami has significantly improved the separation of polynucleotide mixtures based on their molecular weight through Matched Ion Polynucleotide Chromatography and slalom chromatography.

Career Highlights

David W. Togami has built a remarkable career at Transgenomic, Inc., where his research and innovations have led to breakthroughs in genetic analysis and molecular biology. His dedication to improving liquid chromatography systems plays a vital role in research and clinical applications, contributing to more effective and reliable techniques for handling complex biological samples.

Collaborations

Throughout his career, Togami has collaborated with talented professionals such as Douglas T. Gjerde and Robert M. Haefele. These partnerships have fostered an environment of innovation, driving forward the advancements in polynucleotide separation technologies and enhancing the capabilities of liquid chromatography systems.

Conclusion

David W. Togami's inventive spirit and dedication to advancing liquid chromatography have had an enduring impact on the field of molecular biology. With his extensive patent portfolio, particularly his recent innovations in polynucleotide separations, Togami continues to shape the future of analytical techniques, paving the way for new discoveries and applications in scientific research.

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