Company Filing History:
Years Active: 1995-2001
Title: David V Morrissey: Innovator in Nucleic Acid Detection
Introduction
David V Morrissey is a notable inventor based in Middletown, CT (US). He has made significant contributions to the field of nucleic acid detection, holding a total of 4 patents. His innovative methods have advanced the capabilities of hybridization assays, making them more efficient and effective.
Latest Patents
One of Morrissey's latest patents is titled "Immobilized oligonucleotide probes and uses thereof." This invention presents a method for detecting nucleic acids in a sample using oligonucleotide probes that are noncovalently bound to solid supports. This method allows for rapid and sensitive hybridization assays. The process involves coating the support surface with a polynucleotide and hybridizing a specific capture probe for each analyte. The immobilized probes capture nucleic acid targets from complex specimens, enabling nonisotopic detection without prior cell culture or purification. This innovative approach allows for simultaneous testing of multiple specimens, conserving valuable samples and facilitating automation.
Another significant patent is related to "Hybridization promotion reagents." This invention provides novel reagents and methods for their use in nucleic acid hybridization assays. The preferred reagent is a mixture of guanidinium thiocyanate and tetramethylammonium:Trifluoracetate, which enhances hybridization between target nucleic acids and probes. This surprising combination results in superstoichiometric labeling, further improving the detection process.
Career Highlights
Throughout his career, David V Morrissey has worked with prominent companies such as Amoco Corporation and Vysis, Inc. His experience in these organizations has contributed to his expertise in the field of nucleic acid detection and hybridization assays.
Collaborations
Morrissey has collaborated with notable individuals in his field, including Mark L Collins and Kevin R Kearney. These collaborations have likely enriched his work and contributed to the development of his innovative patents.
Conclusion
David V Morrissey is a distinguished inventor whose work in nucleic acid detection has led to significant advancements in hybridization assays. His patents reflect a commitment to innovation and efficiency in scientific research.