Company Filing History:
Years Active: 2000
Title: David Ray Fiipula: Innovator in Arginine Deiminase Research
Introduction
David Ray Fiipula is a notable inventor based in Piscataway, NJ (US). He has made significant contributions to the field of biochemistry, particularly through his work on arginine deiminase derived from Mycoplasma arthritidis. His innovative research has implications for treating various conditions in mammals.
Latest Patents
Fiipula holds a patent for a purified arginine deiminase (ADI) obtained from Mycoplasma arthritidis. This patent includes an isolated nucleic acid molecule containing a nucleotide sequence encoding the amino acid sequence set forth in SEQ ID NO:1. The invention also encompasses an expression vector, a cloned gene for expressing the Mycoplasma arthritidis derived ADI, and recombinant host cells useful in expressing the ADI. Additionally, the patent describes substantially non-antigenic polymer conjugates containing the ADI, which have high levels of retained enzyme activity and relatively long circulating lives.
Career Highlights
Fiipula is associated with Enzon, Inc., where he has been able to apply his expertise in biochemistry and molecular biology. His work has contributed to advancements in therapeutic applications of arginine deiminase.
Collaborations
One of his notable collaborators is Maoliang Wang, with whom he has worked on various projects related to his patent.
Conclusion
David Ray Fiipula's contributions to the field of biochemistry, particularly through his patent on arginine deiminase, highlight his role as an innovator in medical research. His work continues to influence therapeutic strategies for treating conditions in mammals.