David R Liston

Title: David R Liston: Innovator in Fibronectin Type III Binding-Domain Libraries

Introduction

David R Liston is a notable inventor based in San Mateo, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of fibronectin type III binding-domain libraries. With a total of 4 patents, his work has advanced the understanding and application of binding peptides in various biological contexts.

Latest Patents

Among his latest patents, Liston has developed universal fibronectin type III binding-domain libraries. These libraries include fibronectin type III (FN3) polypeptides that are instrumental in identifying binding peptides with high affinities for VEGFR2 or Axl proteins, specifically those exceeding 300 nM. Additionally, he has created walk-through mutagenesis and natural-variant combinatorial FN3 polypeptide libraries, detailing their construction methods and applications. His research has led to the discovery of several high binding affinity polypeptides through screening against selected antigens.

Career Highlights

Throughout his career, David R Liston has worked with various companies, including Protelica, Inc. and Protelix, Inc. His innovative approaches and research have positioned him as a key figure in the biotechnology sector, contributing to advancements in therapeutic applications.

Collaborations

Liston has collaborated with notable professionals in his field, including Craig A Hokanson and Roberto Crea. These partnerships have further enriched his research and development efforts.

Conclusion

David R Liston's contributions to the field of biotechnology, particularly through his patents on fibronectin type III binding-domain libraries, highlight his role as an influential inventor. His work continues to impact the understanding of binding peptides and their applications in medicine.