David Passmore

Title: David Passmore: Innovator in Pharmaceutical Formulations

Introduction

David Passmore is a notable inventor based in Menlo Park, CA (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of formulations related to insulin-like growth factors.

Latest Patents

David Passmore holds 2 patents that showcase his innovative work. His latest patents include "Pharmaceutical formulations for IGF/IGFBP," which disclose new pharmaceutical formulations for the IGF/IGFBP complex. This complex, preferably rhIGF-I/IGFBP-3, is formulated with bulking agents and optionally buffer salts, but without added osmolyte salts. Additionally, he has developed lyophilized formulations for the IGF/IGFBP complex. Another significant patent is related to "Insulin-like growth factor binding protein variants." This invention pertains to variants of native insulin-like growth factor binding protein 3 (IGFBP-3). The disclosed variants are modified to be resistant to hydrolysis and include alterations to the nuclear localization signal (NLS) in native IGFBP-3. Furthermore, amino-terminally extended IGFBP-3s are introduced, which encompass various N-terminal extensions, including peptide and nucleotide binding domains, specific binding members such as ligand binding domains from receptors or antigen binding domains from immunoglobins, and peptide and protein hormones and growth factors.

Career Highlights

David Passmore is associated with Celtrix Pharmaceuticals, Inc., where he continues to advance his research and development efforts in pharmaceuticals. His work has been instrumental in enhancing the understanding and application of insulin-like growth factors in medical treatments.

Collaborations

Throughout his career, David has collaborated with notable professionals in the field, including Stephen Danko and Yasushi Ogawa. These collaborations have contributed to the success and impact of his inventions.

Conclusion

David Passmore is a distinguished inventor whose work in pharmaceutical formulations has the potential to significantly impact medical science. His innovative patents reflect his dedication to advancing healthcare solutions.