Company Filing History:
Years Active: 1999-2000
Title: David O'Reilly: Innovator in Gene Expression and Cloning Technologies
Introduction
David O'Reilly is a notable inventor based in Southampton, GB. He has made significant contributions to the fields of gene expression and DNA cloning, holding a total of 2 patents. His work focuses on enhancing the specificity of gene expression and improving cloning techniques.
Latest Patents
One of O'Reilly's latest patents is titled "Specificity of Gene Expression." This invention aims to improve the specificity of gene expression by targeting a specific expression site of a target gene. The invention provides a chimaeric gene that includes a promoter capable of expressing in multiple regions of the organism. This promoter is linked to an agent that influences the functioning of an endogenous gene in the plant, which is also expressed in various regions. The selection of the promoter and agent ensures an overlap in their expression sites at desired locations, thereby increasing the specificity and targeting of gene expression.
Another significant patent is for the "Direct Cloning of DNA Fragments." This invention involves a vector designed for the direct cloning of products from a PCR protocol. It incorporates single nucleotide overhangs at one or both ends of a linearized DNA segment. These overhangs can be uracil or inosine residues, facilitating the cloning of the desired PCR products.
Career Highlights
Throughout his career, David O'Reilly has worked with several prominent companies, including Novagen, Inc. and Advanced Technologies (Cambridge) Limited. His experience in these organizations has contributed to his expertise in the field of biotechnology.
Collaborations
O'Reilly has collaborated with notable individuals in his field, including Robert C. Mierendorf and Robert E. Novy. These collaborations have likely enriched his research and development efforts.
Conclusion
David O'Reilly is a distinguished inventor whose work in gene expression and cloning technologies has made a significant impact in the field of biotechnology. His innovative patents reflect his commitment to advancing scientific knowledge and practical applications.