Company Filing History:
Years Active: 1979-1985
Title: David Noble: Innovator in Antifungal Compounds
Introduction
David Noble, an accomplished inventor based in Marlow, GB, has made significant contributions to the field of pharmaceuticals with a total of five patents to his name. His work focuses on innovative solutions for medical and agricultural challenges, particularly in antifungal treatments.
Latest Patents
Among Noble's latest patents is the invention of 2-Formyloxymethyl-clavam. This compound is noted for its potential as an antifungal agent that can combat a variety of fungi, providing utility in both medical and horticultural fields. The patent also details processes for isolating this compound from fermentations of the bacterium Streptomyces clavuligerus. Another noteworthy patent involves a pure sodium salt of clavulanic acid, identified as (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]heptane-2-carboxylic acid, along with its salts and pharmaceutical compositions. This invention highlights a purification process for the compound, employing the conversion to its lithium salt in aqueous media and subsequent precipitation.
Career Highlights
David Noble has had an impactful career, contributing his expertise to prominent organizations such as Glaxo Laboratories Limited and Beecham Group plc. His innovative pursuits in these companies have paved the way for advancements in pharmaceutical compounds, especially in the field of antifungal agents.
Collaborations
Throughout his career, Noble has collaborated with esteemed colleagues, including Ian D. Fleming and Wilfred F. Wall. These partnerships have played a vital role in fostering an environment of innovation and creativity, enhancing the development of effective therapeutic solutions.
Conclusion
David Noble's work exemplifies dedication to advancing pharmaceutical innovations. His patents not only reflect his ingenuity but also promise significant benefits to both medical and agricultural sectors. With a focus on antifungal compounds, his contributions will likely continue to influence research and application in the field for years to come.