Title: David Moritz De Kretser: Innovator in Biochemistry
Introduction
David Moritz De Kretser is a notable inventor in the field of biochemistry, particularly recognized for his work on inhibin, a protein that plays a crucial role in reproductive biology. His contributions have significantly advanced the understanding of hormonal regulation in mammals.
Latest Patents
David Moritz De Kretser holds a patent for "Inhibin Isolated From Ovarian Follicular Fluid." This invention describes a protein that meets all biological criteria characteristic of inhibin, isolated from an agonadal source. The patent details the purification and characterization of inhibin, the use of the purified material to raise antibodies, and its applications in both in vitro and in vivo settings. The protein is characterized by an apparent molecular weight of approximately 56,000, an isoelectric point ranging from 6.9 to 7.3, and the ability to bind specifically to Concanavalin A-Sepharose. The protein consists of two sub-units with specific molecular weights and isoelectric points, and it can suppress follicle-stimulating hormone (FSH) in bioassay systems.
Career Highlights
Throughout his career, David Moritz De Kretser has worked with esteemed institutions such as Monash Medical Centre and Inhibin Pty. Limited. His research has contributed to the field of reproductive health and has implications for understanding hormonal functions in mammals.
Collaborations
David has collaborated with notable colleagues, including Henry George Burger and John Kerr Findlay, who have contributed to his research endeavors.
Conclusion
David Moritz De Kretser's innovative work in biochemistry, particularly regarding inhibin, has made a lasting impact on the field of reproductive biology. His contributions continue to influence research and applications in hormonal regulation.