Company Filing History:
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Years Active: 1991
Title: The Innovations of David L Helmreich
Introduction
David L Helmreich is an accomplished inventor based in Ann Arbor, MI (US). He is known for his significant contributions to the field of biotechnology, particularly in the development of microcarrier bead systems for cell culture. His innovative approach has led to advancements that improve cell attachment and proliferation, which are crucial for various applications in research and medicine.
Latest Patents
One of Helmreich's notable patents is for collagen-coated polystyrene microcarrier beads. This invention provides a microcarrier bead system designed for culturing anchorage-dependent cells. The system features a polystyrene core coated with collagen, which can also include proteins such as laminin or fibronectin. The low-density microcarrier bead, with a density of approximately 1.02 g/cc, requires less agitation of the nutrient media to maintain suspension. This reduced stirring minimizes shear forces on the cells, enhancing their attachment and proliferation. The advantages of this microcarrier bead over traditional collagen-only beads or DEAE-dextran coated beads are significant, particularly in reducing contamination during harvesting and minimizing the adsorption of toxins.
Career Highlights
Throughout his career, David L Helmreich has worked with notable organizations, including Solohill Engineering, Inc. and the University of Michigan. His experience in these institutions has allowed him to collaborate with other experts in the field and contribute to groundbreaking research.
Collaborations
Helmreich has collaborated with esteemed colleagues such as William J Hillegas and James Varani. These partnerships have further enriched his work and expanded the impact of his inventions in the scientific community.
Conclusion
David L Helmreich's innovative contributions to biotechnology, particularly through his patented microcarrier bead system, have made a significant impact on cell culture techniques. His work continues to influence research and applications in the field, showcasing the importance of innovation in advancing science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.