Company Filing History:

24 out of 4,942

Hoffmann-la Roche Inc.

where one patent can have more than one assignee

Years Active: 1976-1991

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24 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 5061629 - Production of 2-hydroxy substituted arylalkanoic acids and esters by (1991-10-29),

2. 5037747 - Production of benzopyran-2-carboxylic acids and esters by enzymatic (1991-08-06),

3. 5008411 - Glycidic acid ester and process of preparation (1991-04-16),

4. 4882441 - Lower-alkyl or aryl-sulfonyl unsaturated tacopherols (1989-11-21),

5. 4879395 - Vitamin E intermediate (1989-11-07),

6. 4866205 - Prostaglandin intermediates (1989-09-12),

7. 4853472 - Vitamin E intermediates (1989-08-01),

8. 4789750 - 2-(trimethyl-tridecenyl)-tetramethylchroman intermediates for vitamin E (1988-12-06),

9. 4707555 - Prostaglandin intermediates (1987-11-17),

10. 4558140 - Cyclopenta[b]furan-2-ones (1985-12-10),

11. 4495354 - Process for bicyclic diketones (1985-01-22),

12. 4483990 - Preparation of diketones (1984-11-20),

13. 4247712 - Preservation of aqueous systems with 2-chloro-3-oxobutyramide derivatives (1981-01-27),

14. 4247690 - Lasalocid derivatives (1981-01-27),

15. 4217363 - Preservation of aqueous systems with (1980-08-12),

Title: A Comprehensive Look at the Innovations of David L Coffen

Introduction

David L Coffen, an accomplished inventor based in Glen Ridge, NJ, holds an impressive 24 patents to his name. His contributions to the field of chemistry, particularly in the area of enzymatic processes, have paved the way for advancements in various applications. This article delves into his latest patents, notable career highlights, and collaborations throughout his professional journey.

Latest Patents

Coffen’s recent innovations include methods for producing enantiomerically pure 2-hydroxy substituted arylalkanoic acids and their esters. This process utilizes Pseudomonas lipase in a controlled pH environment, facilitating the hydrolysis of racemic 2-hydroxy arylalkanoic acid esters. Additionally, he has developed a method for the production of benzopyran-2-carboxylic acids and esters, again relying on Pseudomonas lipase for selective hydrolysis. These advancements reflect Coffen's expertise and commitment to enhancing biochemical processes through innovative techniques.

Career Highlights

Throughout his career, David L Coffen has made significant impacts while working with notable companies in the industry. His tenure includes positions at Hoffmann-La Roche Inc. and Givaudan Corporation, where he has been instrumental in advancing research and development efforts. His innovations continue to influence the pharmaceutical and biochemical sectors.

Collaborations

Coffen’s journey has also involved fruitful collaborations with esteemed colleagues such as Harold A Brandman and Milton Manowitz. These partnerships have fostered a conducive environment for innovation, enabling the exploration of new ideas and technologies in chemistry.

Conclusion

David L Coffen's contributions to the scientific community through his 24 patents underscore his role as a leading inventor in his field. His work, characterized by groundbreaking enzymatic processes and collaborations with prominent industry figures, reflects a dedication to innovation and excellence. As he continues to push the boundaries of chemical research, his legacy will undoubtedly inspire future generations of inventors.

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