Location History:
- Ft. Lauderdale, FL (US) (1981)
- Fort Lauderdale, FL (US) (1981 - 1982)
Company Filing History:
Years Active: 1981-1982
Title: David L Chastain, Jr: Innovator in Blood Reference Controls
Introduction
David L Chastain, Jr. is a notable inventor based in Fort Lauderdale, FL (US). He has made significant contributions to the field of medical technology, particularly in the preparation of whole blood reference controls. With a total of four patents to his name, Chastain's work has had a lasting impact on devices that utilize electronic means for whole blood determinations.
Latest Patents
One of Chastain's latest patents involves a process for preparing whole blood reference controls that maintain long-term stability for up to six months. This innovative process is crucial for devices that determine platelet count, mean cell volume, and red blood distribution width. The preconditioning diluent for the red blood cells consists of an aqueous solution of lactose, sodium azide, and a non-ionic surfactant, which is pH buffered and osmolality adjusted. The media for the whole blood control includes lactose, fungicides, antibiotics, and supplementary agents such as purine nucleosides. Additionally, the process incorporates components that alter red blood cell membranes, including bile salts, cholic acid derivatives, and phenothiazine compounds. The red blood cells are separated from the whole blood and preconditioned to achieve the desired size distribution width and volume before being mixed in the media to yield the desired cell count for the whole blood reference control.
Career Highlights
Chastain has been associated with Coulter Electronics, Inc., where he has furthered his research and development efforts. His work has been instrumental in advancing the technology used in blood analysis and diagnostics.
Collaborations
Chastain has collaborated with notable coworkers such as Stephen L Ledis and Harold R Crews, contributing to the innovative environment at Coulter Electronics, Inc.
Conclusion
David L Chastain, Jr. is a distinguished inventor whose work in blood reference controls has significantly advanced medical technology. His innovative processes and collaborations continue to influence the field of blood diagnostics.