Company Filing History:
Years Active: 1994-1998
Title: **Innovator Spotlight: David L. Barker of Foster City, CA**
Introduction
David L. Barker is an accomplished inventor based in Foster City, California. With a notable portfolio comprising three patents, he stands out in the field of capillary electrophoresis, making significant contributions to the separation of nucleic acids.
Latest Patents
Among his latest patents is the innovative "Denaturing Separation Matrix Having Hydroxyethyl Cellulose for Nucleic Acids." This advanced capillary electrophoresis separation matrix is specifically designed for single-stranded nucleic acids, enhancing the processes of DNA sizing and sequencing. The matrix, which combines hydroxyethyl cellulose with urea and preferably includes formamide, creates optimal denaturing conditions. Remarkably, it achieves single-base resolution for sequences up to approximately 500 base pairs. The separation matrix is not only cost-effective and simple to prepare, but it also eliminates the need for polymerization steps. Additionally, its low viscosity facilitates easy pumping in and out of capillary tubes, allowing for high throughput and the reuse of these tubes across multiple separations.
Career Highlights
David L. Barker is currently affiliated with Molecular Dynamics Limited, where he applies his expertise in developing innovative solutions for biochemical applications. His work has advanced the capabilities of nucleic acid analysis, significantly impacting the efficiency and effectiveness of genetic research.
Collaborations
Throughout his career, Barker has collaborated with esteemed colleagues, including Richard F. Johnston and John S. Bashkin. These partnerships have fostered a dynamic environment for innovation and have contributed to the successful development of his patents.
Conclusion
David L. Barker’s innovative work in capillary electrophoresis demonstrates his commitment to advancing scientific understanding and technology in nucleic acid research. His contributions, characterized by cost-effective and efficient solutions, continue to shape the landscape of genetic analysis, affirming his status as a leading inventor in his field.