This inventor holds 7 USPTO granted patents and 4 published patent applications and 1 EPO patent. Top assignee: University of Pittsburgh. Active years: 1999-2023.
Location History:
- Pittsburgh, PA (US) (1999)
- Sewickley, PA (US) (2009 - 2023)
Company Filing History:
Years Active: 1999-2023
Title: David Krisky: Innovator in Electrophysiological Modulation
Introduction
David Krisky is a notable inventor based in Sewickley, PA (US). He has made significant contributions to the field of electrophysiology, particularly in the modulation of glycine receptors. With a total of 7 patents to his name, Krisky's work has the potential to impact pain management and cellular activity.
Latest Patents
One of Krisky's latest patents focuses on the targeted delivery of glycine receptors to excitable cells. This invention provides a method for modulating the electrophysiological activity of excitable cells by causing exogenous expression of a glycine receptor (GlyR) protein. The method involves exposing the excitable cell to an allosteric modulator of the GlyR protein, which in turn modulates the electrophysiological activity of the cell. This innovative approach can be utilized to control pain in subjects. Additionally, the invention includes a replication-defective HSV vector that comprises an expression cassette encoding a GlyR protein, along with stocks and pharmaceutical compositions containing such vectors, and a transgenic animal.
Career Highlights
Throughout his career, David Krisky has worked with esteemed organizations such as the University of Pittsburgh and the United States Government, represented by the Department of Veterans Affairs. His work in these institutions has allowed him to further his research and contribute to advancements in medical science.
Collaborations
Krisky has collaborated with notable colleagues, including Joseph C. Glorioso III and Michael Cascio. These partnerships have enriched his research and expanded the impact of his inventions.
Conclusion
David Krisky's innovative work in the modulation of glycine receptors showcases his dedication to advancing medical science. His contributions have the potential to significantly improve pain management and cellular function.