David Knowles

Title: David Knowles: Innovator in Cancer Risk Assessment

Introduction

David Knowles is a notable inventor based in Menlo Park, CA. He has made significant contributions to the field of cancer research, particularly in assessing the risk of breast cancer recurrence. With a total of 3 patents to his name, Knowles has developed innovative systems and methods that integrate large amounts of prognostic information to improve patient outcomes.

Latest Patents

One of Knowles' latest patents focuses on assessing the risk of breast cancer recurrence. This patent presents systems and computer-implemented methods that utilize a holistic integration of extensive prognostic information into a single comparative prognostic dataset. The risk classification system is trained using a large amount of information from a cohort of training slides from several patients, along with their survival data. A machine-learning-based binary classifier is employed to analyze granular image features from multiple slides corresponding to cancer patients whose survival information is known. This trained classifier can then classify image features from test patients into low-risk or high-risk groups.

Career Highlights

Throughout his career, David Knowles has worked with prominent organizations such as Ventana Medical Systems, Inc. and Leland Stanford Junior University. His work has been instrumental in advancing the understanding of cancer prognosis and improving the tools available for clinicians.

Collaborations

Knowles has collaborated with several professionals in his field, including Michael S. Barnes and Srinivas Chukka. These collaborations have contributed to the development of innovative solutions in cancer risk assessment.

Conclusion

David Knowles is a distinguished inventor whose work in cancer risk assessment has the potential to significantly impact patient care. His innovative approaches and collaborations continue to drive advancements in the field of oncology.