This inventor holds 2 USPTO granted patents. Top assignee: Pfizer Corporation. Active years: 1997-2001.
Company Filing History:
Years Active: 1997-2001
Title: The Innovations of David K Kreutter
Introduction
David K Kreutter is a notable inventor based in Madison, CT (US). He has made significant contributions to the field of biomedical research, particularly in the development of transgenic animal models and treatments for various diseases. With a total of 2 patents, Kreutter's work has the potential to impact the treatment of serious health conditions.
Latest Patents
Kreutter's latest patents include groundbreaking innovations. One of his patents focuses on "Transgenic animal models for type II diabetes mellitus." This invention describes the generation of transgenic animal models for testing various treatments of Type II Diabetes Mellitus. The DNA construct allows pancreatic β cell-specific expression of human islet associated polypeptide (IAPP) under the regulation of the rat insulin II promoter in both cell lines and transgenic animals. The transgenic animals develop amyloid plaque deposits in the islets of Langerhans in the pancreas, fasting hyperglycemia, glycouria, and diabetic glomerulosclerosis at 3 to 5 months of age. This model can be used to screen treatments that inhibit expression of human IAPP and to evaluate therapies that affect the progression of the disease phenotype.
Another significant patent is related to ".beta..sub.3 -Adrenoceptor agonists and antagonists for the treatment of intestinal motility disorders." This invention outlines methods for treating intestinal motility disorders, inflammatory bowel disease, and gastrointestinal ulcerations by administering a .beta..sub.3 -adrenoceptor antagonist or agonist. This work has the potential to improve the quality of life for patients suffering from these conditions.
Career Highlights
Kreutter's career has been marked by his dedication to research and innovation. He has worked with Pfizer Corporation, where he has been able to apply his expertise in developing new treatments and models for various diseases. His contributions to the field have been recognized and have paved the way for further advancements in biomedical research.
Collaborations
Throughout his career, Kreutter has collaborated with esteemed colleagues, including Robert L Dow and Walter C Soeller. These collaborations have enhanced his research and have contributed to the successful development of his patents.
Conclusion
David K Kreutter is a prominent inventor whose work in the field of biomedical research has led to significant advancements in the treatment of diabetes and gastrointestinal disorders. His innovative