Company Filing History:
Years Active: 1999-2004
Title: David J Sherratt: Innovator in Plasmid Stabilization
Introduction
David J Sherratt is a notable inventor based in Witney, GB. He has made significant contributions to the field of gene therapy and recombinant protein production. With a total of two patents to his name, Sherratt's work focuses on innovative systems that enhance the stability and functionality of plasmids.
Latest Patents
Sherratt's latest patents revolve around a novel system of repressor titration for the maintenance of plasmids. This system is particularly useful in gene therapy and the production of recombinant proteins. It involves a transformed host cell containing a plasmid with an operator that can bind to a repressor expressed in trans. The system includes a first chromosomal gene encoding the repressor and a second chromosomal gene that is essential for cell growth. The plasmid is maintained in sufficient numbers to titrate the repressor, ensuring the essential gene is expressed, which permits cell growth.
Career Highlights
Throughout his career, David J Sherratt has worked with several prominent companies, including Cobra Biologics Limited and Cobra Therapeutics Limited. His experience in these organizations has allowed him to develop and refine his innovative ideas in the field of biotechnology.
Collaborations
Some of his notable coworkers include Steven Geraint Williams and Julian A J Hanak. Their collaboration has likely contributed to the advancement of research and development in their respective fields.
Conclusion
David J Sherratt's contributions to plasmid stabilization and gene therapy highlight his role as an influential inventor in biotechnology. His innovative systems continue to pave the way for advancements in medical research and applications.