David Fred McComsey

Title: Innovations of David Fred McComsey

Introduction

David Fred McComsey is a notable inventor based in Philadelphia, PA. He has made significant contributions to the field of chemistry, particularly in the development of methods for synthesizing important compounds. With a total of two patents to his name, McComsey's work has implications in pharmacology and organic chemistry.

Latest Patents

One of McComsey's latest patents is focused on the reduction of indole compounds to indoline compounds. This method describes a process for reducing indole compounds using a borane complex reagent in the presence of trifluoroacetic acid. The technique is efficient and minimizes undesirable side reactions, making it an excellent approach for preparing specific indoline compounds. Additionally, he has developed a novel dioxyborane that serves as a useful borane reagent. His other patent involves substituted thioindoles and their derivatives, which are valuable as cardiac rate-lowering agents and have various pharmacological properties.

Career Highlights

David Fred McComsey is associated with McNeil Laboratories, Incorporated, where he applies his expertise in chemistry to advance research and development. His innovative methods and discoveries have contributed to the company's mission of improving health outcomes through scientific advancements.

Collaborations

Throughout his career, McComsey has collaborated with esteemed colleagues, including Michael John Zelesko and Bruce E Maryanoff. These partnerships have fostered a collaborative environment that enhances the research and development process.

Conclusion

David Fred McComsey's contributions to the field of chemistry through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the pharmaceutical industry and advance scientific knowledge.