Company Filing History:
Years Active: 2003-2010
Title: Innovations by David E Modrak
Introduction
David E Modrak is a notable inventor based in Nutley, NJ (US). He has made significant contributions to the field of medicine, particularly in the treatment of autoimmune diseases and tumor therapies. With a total of three patents to his name, Modrak's work is paving the way for new therapeutic approaches.
Latest Patents
One of Modrak's latest patents is focused on sphingomyelin therapy for autoimmune diseases. This invention suggests that the therapy in patients treated with apoptosis-inducing agents can be enhanced by co-administration of sphingomyelin. The combination is believed to improve an autoimmune disease cell's ability to undergo ceramide-induced apoptosis by increasing sphingomyelin levels in all cellular compartments. This provides sufficient substrate for activated sphingomyelinase. In alternative embodiments, sphingomyelin may be administered alone, in combination with corticosteroids, or alongside an apoptosis-inducing agent. Another significant patent involves the enhancement of tumor therapy through the co-administration of sphingomyelin. This invention likely improves a tumor cell's ability to undergo ceramide-induced apoptosis by increasing sphingomyelin levels, thereby providing the necessary substrate for activated sphingomyelinase. Additionally, a method for treating rheumatoid arthritis is also included in this patent.
Career Highlights
David E Modrak is associated with the Center for Molecular Medicine and Immunology, where he continues to innovate and contribute to medical research. His work is characterized by a strong focus on enhancing therapeutic outcomes for patients suffering from complex diseases.
Collaborations
Modrak collaborates with David M Goldenberg, further enriching his research endeavors and expanding the impact of their work in the medical field.
Conclusion
David E Modrak's innovative patents and contributions to medical science highlight his commitment to improving patient care through advanced therapies. His work continues to inspire future research and development in the field.