Company Filing History:
Years Active: 2003-2016
Title: Innovations of David E Gindelberger in Metathesis Catalysts
Introduction
David E Gindelberger is a notable inventor based in South Pasadena, CA, with a significant contribution to the field of chemistry. He holds a total of six patents, showcasing his innovative approach to the synthesis of metathesis catalysts. His work has implications for various chemical reactions, making him a key figure in this area of research.
Latest Patents
Gindelberger's latest patents focus on chelating carbene ligand precursors and their application in the synthesis of metathesis catalysts. These catalysts are air-stable monomeric species that can efficiently promote various metathesis reactions. They can be recovered from the reaction mixture and reused, which adds to their practicality. The use of internal olefin compounds, specifically beta-substituted styrenes, as ligand precursors is a significant advancement. These compounds are easier and less costly to prepare compared to terminal olefin compounds, such as unsubstituted styrenes. Additionally, they are more stable and less prone to spontaneous polymerization. Gindelberger's methods also eliminate the need for CuCl by replacing it with organic acids, mineral acids, mild oxidants, or even water, resulting in high yields of Hoveyda-type methathesis catalysts. His innovative approach provides an efficient method for preparing these catalysts by reacting a suitable ruthenium complex in high concentrations of the ligand precursors, followed by crystallization from an organic solvent.
Career Highlights
Throughout his career, Gindelberger has worked with various companies, including Materia, Inc. His experience in the industry has allowed him to apply his innovative ideas in practical settings, contributing to advancements in chemical synthesis.
Collaborations
Gindelberger has collaborated with notable colleagues, including Richard L Pederson and Jason K Woertink. These collaborations have likely enriched his research and contributed to the development of his patents.
Conclusion
David E Gindelberger's contributions to the field of metathesis catalysts through his innovative patents highlight his role as a significant inventor. His work not only advances chemical synthesis but also demonstrates the importance of practical applications in scientific research.