Company Filing History:
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Years Active: 2008-2017
Title: The Innovative Contributions of David Clapham
Introduction
David Clapham, based in Wellesley, Massachusetts, has emerged as a prominent inventor with a significant portfolio of 12 patents. His work primarily focuses on advancing our understanding of cation channels in sperm and proton channels, contributing to fields such as reproductive medicine and cellular biology.
Latest Patents
Among his latest innovations are patents related to the sperm-specific cation channel, known as CatSper2. This invention encompasses nucleic acid and protein sequences that are specifically expressed in sperm. The CatSper2 protein plays a crucial role in various biological functions. The disclosures include methods for in vitro fertilization, contraception, and identifying modulators of CatSper2 activity. Furthermore, Clapham has developed methods for genotyping subjects concerning CatSper2, as well as diagnosing and treating disorders related to CatSper2, including infertility.
In addition to his work on CatSper2, Clapham has also focused on voltage-gated Hv1 proton channels. His patents include nucleic acid and protein sequences related to this channel, as well as techniques for diagnosing and treating disorders mediated by Hv1. His research has implications for understanding intracellular pH changes and developing potential therapeutic approaches in this domain.
Career Highlights
Clapham has made significant strides in his career, having worked with esteemed organizations like Children's Medical Center Corporation and the University of Texas System. His research has not only led to a multitude of patents but has also advanced scientific understanding in critical areas of health and medicine.
Collaborations
Throughout his career, Clapham has collaborated with notable colleagues, including Dejian Ren and Magdalene M. Moran. These partnerships have been instrumental in furthering innovative health solutions and enhancing research methodologies.
Conclusion
David Clapham stands as a notable figure in the realm of scientific innovation. His extensive research and numerous patents reflect his commitment to exploring complex biological mechanisms and translating that knowledge into practical applications. As the medical field continues to evolve, Clapham's contributions may pave the way for groundbreaking advancements in reproductive health and beyond.