Location History:
- Alexandria, VA (US) (1998 - 2003)
- Honolulu, HI (US) (2014)
- Monroe, NJ (US) (2024)
Company Filing History:
4 out of 484 
1 out of 265 
Years Active: 1998-2024
Title: Innovations of David C Fritzinger
Introduction
David C Fritzinger is a notable inventor based in Alexandria, VA (US). He has made significant contributions to the field of biotechnology, particularly in the development of modified human complement proteins. With a total of 6 patents to his name, Fritzinger's work has the potential to impact various medical treatments.
Latest Patents
Fritzinger's latest patents include innovative approaches to modulating complement function. One of his key inventions involves a modified human C3 protein that features several single amino acid changes. This modification is designed to enhance the protein's affinity to factor B or Bb while reducing its affinity to factor H. Additionally, the modified protein aims to decrease immunogenicity compared to the native human C3 protein. The patent also covers a nucleotide sequence encoding this modified C3 protein, along with methods for depleting complement in patients and ameliorating conditions such as reperfusion injury.
Another significant patent focuses on human complement C3 derivatives that exhibit cobra venom factor-like functions. This modified C3 protein incorporates portions of a Cobra Venom Factor protein, resulting in enhanced stability and reduced immunogenicity. The patent outlines methods for treating diseases associated with increased complement activation, including autoimmune diseases and reperfusion injury.
Career Highlights
Fritzinger has worked with prestigious institutions such as Georgetown University and the University of Hawai'i. His research has contributed to advancements in therapeutic strategies that leverage the complement system for medical applications.
Collaborations
Fritzinger has collaborated with notable professionals in his field, including Carl-Wilhelm Ernst Vogel and Reinhard Bredehorst. Their combined expertise has furthered the development of innovative solutions in biotechnology.
Conclusion
David C Fritzinger's contributions to the field of biotechnology through his patents and collaborations highlight his role as a significant inventor. His work continues to pave the way for advancements in medical treatments and therapeutic strategies.