This inventor holds 2 USPTO granted patents and 12 published patent applications, plus 2 CIPO patents and 1 EPO patent. Top assignee: Amgen Inc.. Active years: 1999-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1999-2023
Title: David Brems: Innovator in Pharmaceutical Protein Formulations
Introduction
David Brems is a notable inventor based in Newbury Park, CA (US). He has made significant contributions to the field of pharmaceutical formulations, particularly in the development of self-buffering protein formulations. With a total of 2 patents, his work has the potential to impact both veterinary and human medical applications.
Latest Patents
One of Brems' latest patents is focused on self-buffering antibody formulations. This invention provides self-buffering pharmaceutical protein formulations that are suitable for both veterinary and human medical use. The formulations are designed to maintain a stable pH over extended periods, which is crucial for the distribution and storage of pharmaceutical proteins. This innovation avoids the disadvantages associated with conventional buffering agents, making it a significant advancement in the field.
Another important patent by Brems relates to stable protein: phospholipid compositions and methods. This invention stabilizes proteins against thermally-induced aggregation and loss of activity by contacting them with negatively charged lipid vesicles. The resulting protein:phospholipid complex preserves the protein's secondary and tertiary structure, making it useful in high-temperature formulations and novel delivery vehicles.
Career Highlights
David Brems is currently associated with Amgen Inc., a leading biotechnology company. His work at Amgen has allowed him to focus on innovative solutions in the pharmaceutical industry, particularly in the area of protein formulations.
Collaborations
Brems has collaborated with notable colleagues such as David S. Collins and Younsik Cha. These collaborations have likely contributed to the advancement of his research and the successful development of his patents.
Conclusion
David Brems is a prominent inventor whose work in self-buffering protein formulations and stable protein compositions has the potential to revolutionize pharmaceutical applications. His contributions to the field are significant and demonstrate the importance of innovation in medical science.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile