David Benjamin Buckley

Title: David Benjamin Buckley: Innovator in Hepatocyte Research

Introduction

David Benjamin Buckley is a notable inventor based in Olathe, KS (US). He has made significant contributions to the field of drug metabolism and transport through his innovative research. With a total of 3 patents, Buckley has focused on developing in vitro test systems that evaluate the effects of xenobiotics on human hepatocytes.

Latest Patents

Buckley's latest patents include a groundbreaking in vitro test system designed to evaluate xenobiotics as immune-modulators of drug transport and metabolism in human hepatocytes. This method allows for the assessment of how a xenobiotic, such as a drug, influences drug metabolism in hepatocytes. The kit consists of a culture of hepatocytes, a portion of an in vitro xenobiotic-stimulated biological sample, and detailed instructions for incubating the hepatocytes with the sample. This innovative approach enables researchers to analyze the activity and expression of biomarkers in the hepatocytes, providing valuable insights into the effects of xenobiotics on drug metabolism.

Career Highlights

David Benjamin Buckley is currently associated with Xenotech, L.L.C., where he continues to advance his research in hepatocyte studies. His work has been instrumental in enhancing the understanding of drug interactions and metabolism, which is crucial for the development of safer and more effective pharmaceuticals.

Collaborations

Throughout his career, Buckley has collaborated with talented professionals in his field, including Maciej Czerwinski and Faraz Kazmi. These collaborations have further enriched his research and contributed to the success of his innovative projects.

Conclusion

David Benjamin Buckley stands out as a prominent inventor in the realm of hepatocyte research, with a focus on the effects of xenobiotics on drug metabolism. His contributions through patents and collaborations continue to shape the future of pharmaceutical research and development.