David B Collinge

Title: David B Collinge: Innovator in Terpenoid Synthesis

Introduction

David B Collinge is a notable inventor based in Frederiksberg, Denmark. He has made significant contributions to the field of biochemistry, particularly in the synthesis of sesquiterpenes. His innovative work has led to the development of methods that utilize fungal enzymes for producing valuable compounds.

Latest Patents

David B Collinge holds a patent titled "Method for producing the sesquiterpene viridiflorol with a fungal enzyme." This patent describes constructs, host cells, fungi, seeds, plants, and methods that include a terpenoid synthase (SiTPS). The invention highlights the use of a basidionycete, a non-specific-host root endophyte fungus, which possesses a functional terpenoid synthase gene. Heterologous expression of SiTPS in host cells has demonstrated that the produced protein efficiently utilizes the fifteen-carbon precursor farnesylpyrophosphate (FTP) to synthesize the sesquiterpene alcohol viridiflorol.

Career Highlights

Throughout his career, David B Collinge has worked with prestigious institutions such as Michigan State University and the University of Copenhagen. His research has focused on the biochemical pathways involved in terpenoid synthesis, contributing to advancements in the field.

Collaborations

David has collaborated with notable colleagues, including Fani Ntana and Björn Hamberger. Their joint efforts have furthered the understanding of fungal enzymes and their applications in producing valuable natural products.

Conclusion

David B Collinge's innovative work in the synthesis of sesquiterpenes showcases his expertise and dedication to advancing biochemistry. His contributions have the potential to impact various industries, particularly in the production of natural compounds.