David A Agard

Title: Innovations and Contributions of David A. Agard

Introduction

David A. Agard is a prominent inventor based in Burlingame, California. He has made significant contributions to the field of cryo-electron microscopy (cryo-EM) and has been awarded a total of 9 patents. His work focuses on enhancing the analysis of diverse samples through innovative methodologies.

Latest Patents

One of Agard's latest patents is titled "Graphene oxide affinity sample grids for Cryo-EM." This innovation enables facile cryo-EM analysis by functionalizing sample grids with affinity molecules that efficiently concentrate sample molecules away from the air-water interface. The methods described include creating high-quality graphene oxide films on cryo-EM substrates, which are essential for capturing diverse sample types with high affinity. Additionally, spacers such as PEG chains are utilized to reduce substrate-induced artifacts.

Another notable patent is for a "Structured illumination microscope apparatus and an image forming apparatus." This invention involves the conversion of polarized light emitted from an optical fiber into nearly linear polarized light. The structured illumination light is generated by separating the light into diffracted components using a diffraction grating, enhancing the imaging capabilities of the apparatus.

Career Highlights

David A. Agard has had a distinguished career, working with esteemed institutions such as the University of California and Yeda Research and Development Company. His expertise in cryo-EM and microscopy has positioned him as a leader in his field, contributing to advancements in scientific research and technology.

Collaborations

Throughout his career, Agard has collaborated with notable colleagues, including John W. Sedat and Zvi Kam. These partnerships have fostered innovation and have led to significant advancements in their respective areas of research.

Conclusion

David A. Agard's contributions to the field of cryo-EM and microscopy are noteworthy, with several patents that enhance the analysis of diverse samples. His innovative approaches and collaborations continue to influence the scientific community positively.