Company Filing History:
Years Active: 2014
Title: The Innovative Contributions of Dar-Fu Tai
Introduction
Dar-Fu Tai is a notable inventor based in Hualien, Taiwan. He has made significant contributions to the field of chemistry, particularly in the synthesis of optically active compounds. His work is characterized by a meticulous approach to chemical processes, leading to innovative solutions in the industry.
Latest Patents
Dar-Fu Tai holds a patent for a process for preparing optically active antrocin. This invention outlines a method that begins with the introduction of the correct configuration of trans-decalone. The process utilizes alkyl aluminum/TMSCN to react with decalenone, resulting in racemic nitrile-decalone. This compound is then resolved with chiral diol through ketalization, producing two chromatography separable diasteromers. Following a simple column chromatography, optically pure compounds are obtained. A critical step in this synthesis is formylation for lactone formation, with the remainder of the synthesis being straightforward through oxidation and olefination. The total synthesis is completed in 10 steps with a 7% overall yield from commercially available 6-methoxy-2-tetralone.
Career Highlights
Dar-Fu Tai is associated with Deyew Biotech Corp., where he applies his expertise in chemical synthesis. His innovative work has contributed to advancements in the preparation of optically active compounds, showcasing his skills as a leading inventor in his field.
Collaborations
Dar-Fu Tai has collaborated with notable colleagues, including Venkatachalam Angamuthu and Yew-Min Tzeng. These collaborations have further enhanced his research and development efforts in the biotechnology sector.
Conclusion
Dar-Fu Tai's contributions to the field of chemistry, particularly through his patent for the preparation of optically active antrocin, highlight his innovative spirit and dedication to advancing scientific knowledge. His work continues to influence the industry and inspire future innovations.