Location History:
- Nijmegen, NL (2019)
- Malden, NL (2011 - 2020)
Company Filing History:
4 out of 5 
1 out of 818 
1 out of 1 Years Active: 2011-2020
Title: Discovering the Innovations of Daphne Hessels
Introduction
Daphne Hessels, an accomplished inventor based in Malden, Netherlands, has made significant contributions to the field of medical diagnostics, particularly in prostate cancer research. With a total of six patents to her name, she has developed innovative methods and compositions that enhance the prognosis and treatment of this prevalent disease.
Latest Patents
Daphne’s most recent patents focus on advanced prognostic compositions and kits for prostate cancer. One notable invention describes methods that include determining the ratio of PCA3 and a prostate-specific marker expression in a urine sample. This analysis correlates the PCA3/prostate-specific marker ratio with the aggressiveness and mortality risk of prostate cancer in patients.
Another significant innovation involves a method for detecting DLX1 mRNA, HOXC6 mRNA, and KLK3 mRNA in urine samples. This invention predicts and aids in the treatment of clinically significant prostate cancer in individuals suspected of having the disease, particularly those with a Gleason score of seven or more and a serum prostate-specific antigen level lower than 15 ng/ml. The method establishes cancer prognosis through normalized expression analysis of critical prostate tumor markers.
Career Highlights
Daphne has collaborated with renowned institutions and organizations throughout her career. She has worked at Stichting Katholieke Universiteit, the University Medical Centre Nijmegen, and Gen-Probe, Inc. These affiliations have allowed her to merge research and practical applications, leading to meaningful advancements in cancer diagnostics.
Collaborations
Throughout her career, Daphne has collaborated with esteemed colleagues such as Jack A. Schalken and Gerald Verhaegh. Their collective expertise has further propelled her research and the development of her innovative patents in the realm of prostate cancer prognosis and treatment.
Conclusion
Daphne Hessels stands out as a pioneering inventor in the medical field, with her significant contributions to prostate cancer diagnostics. Her innovative methods and compositions demonstrate a commitment to improving patient outcomes through advanced research and collaboration. With her continued dedication to innovation, Daphne is poised to make further strides in the healthcare industry.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.