Location History:
- Siena, IT (2010)
- Narni, IT (2012)
Company Filing History:
Years Active: 2010-2012
Title: Daniela Proietti: Innovator in Saccharide Vaccine Analysis
Introduction
Daniela Proietti is a notable inventor based in Narni, Italy. She has made significant contributions to the field of vaccine analysis, particularly focusing on saccharide vaccines. With a total of 2 patents, her work has advanced the methods used in vaccine quality control.
Latest Patents
One of her latest patents is titled "Analysis of saccharide vaccines without interference." This invention introduces methods that allow for the analysis of mixed meningococcal saccharides from multiple serogroups, despite their shared monosaccharide units. By combining saccharides from serogroups C, W135, and Y, the invention effectively analyzes the content of sialic acid, glucose, and galactose. The results for glucose and galactose are utilized to quantify saccharides from serogroups Y and W135, respectively. The combined glucose and galactose content is then subtracted from the sialic acid content to determine the saccharides from serogroup C. This innovative method enables the resolution of the three serogroups, even with overlapping monosaccharide contents. Furthermore, the analysis can be performed on the same material without interference from other saccharide materials, simplifying the quality control of vaccines containing capsular saccharides from multiple serogroups.
Another significant patent is "Analysis of liquid chromatography eluates." In this invention, the analysis of saccharides by High-Performance Anion-Exchange Chromatography (HPAEC) is enhanced by coupling amperometric detection with ultraviolet detection. This dual detection method provides a more comprehensive analysis of the eluate from a liquid chromatography column, yielding information that surpasses what can be obtained from either detection method alone.
Career Highlights
Throughout her career, Daniela Proietti has worked with prominent companies in the pharmaceutical industry, including Novartis AG and Novartis Vaccines and Diagnostics Srl. Her experience in these organizations has contributed to her expertise in vaccine development and analysis.
Collaborations
Daniela has collaborated with notable colleagues such as Angela Bardotti and Stefano Ricci. These partnerships have further enriched her work and innovations in the field.
Conclusion
Daniela Proietti's contributions to the analysis of saccharide vaccines have significantly impacted vaccine quality control