Company Filing History:
3 out of 38 
1 out of 7 Years Active: 2000-2006
Title: Daniela Gutman: Innovator in Pharmaceutical Chemistry
Introduction
Daniela Gutman is a prominent inventor based in Rishon Lezion, Israel. She has made significant contributions to the field of pharmaceutical chemistry, particularly in the area of ureide alkylation. With a total of four patents to her name, her work has the potential to impact various therapeutic applications.
Latest Patents
One of her latest patents is titled "Method and reagents for N-alkylating ureides." This innovative method involves reacting a ureide with an alkylating agent in the presence of a basic catalyst within an aprotic reaction medium. The ureide can be a 5,5-disubstituted barbituric acid, phenytoin, glutethimide, or ethosuximide. The alkylating agent used is an ester of a sulfonic acid, and the base may be a hydride or amine. A preferred process includes N-alkoxyalkylating 5,5-diphenyl-barbituric acid with methoxymethyl methanesulfonate, resulting in the isolation of N,N'-bismethoxymethyl-5,5-diphenyl-barbituric acid. Additionally, her invention introduces novel compounds such as N-methoxymethyl-5,5-diphenylbarbituric acid, N-methoxymethyl ethosuximide, and N-methoxymethyl glutethimide, along with methods for administering these compounds to patients.
Career Highlights
Throughout her career, Daniela has worked with notable companies, including Taro Pharmaceutical Industries Limited and Taro Pharmaceuticals. Her experience in these organizations has allowed her to refine her skills and contribute to significant advancements in pharmaceutical research.
Collaborations
Daniela has collaborated with various professionals in her field, including her coworker Hershel Herzog. These collaborations have fostered an environment of innovation and have led to the development of her impactful patents.
Conclusion
Daniela Gutman is a remarkable inventor whose work in pharmaceutical chemistry continues to pave the way for new therapeutic solutions. Her innovative methods and compounds hold promise for future advancements in medicine.
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