Location History:
- Carlsbad, CA (US) (2005)
- Solana Beach, CA (US) (2009 - 2010)
- San Diego, CA (US) (2011)
Company Filing History:
Years Active: 2005-2011
Title: Innovations of Daniel T Connolly
Introduction
Daniel T Connolly is a notable inventor based in Solana Beach, CA (US). He has made significant contributions to the field of biomedical research, particularly in the area of G protein-coupled receptors (GPCRs). With a total of 4 patents, Connolly's work focuses on developing therapeutic agents for various cardiovascular and metabolic disorders.
Latest Patents
Connolly's latest patents include groundbreaking inventions aimed at treating cardiovascular disorders. One of his notable patents is titled "Human G protein-coupled receptor and modulators thereof for the treatment of cardiovascular disorders." This invention outlines methods for identifying candidate compounds that can modulate GPCRs, specifically those expressed by cardiomyocytes. The patent emphasizes the potential of inverse agonists and antagonists as therapeutic agents for heart diseases, including hypertrophic cardiomyopathy and congestive heart failure.
Another significant patent is "Human G protein-coupled receptors for metabolic-related disorders." This invention focuses on GPCRs that are coupled to Gi and lower intracellular cAMP levels. It highlights the use of agonists as therapeutic agents for metabolic-related disorders such as dyslipidemia, atherosclerosis, and type 2 diabetes.
Career Highlights
Daniel T Connolly is currently associated with Arena Pharmaceuticals, Inc., where he continues to innovate in the field of drug development. His work has been instrumental in advancing the understanding of GPCRs and their role in various diseases. Connolly's research has the potential to lead to new treatments that can significantly improve patient outcomes.
Collaborations
Connolly has collaborated with esteemed colleagues, including David J Unett and Ruoping Chen. These collaborations have further enriched his research and contributed to the development of innovative therapeutic solutions.
Conclusion
Daniel T Connolly's contributions to the field of biomedical research through his patents and collaborations highlight his commitment to advancing medical science. His work on GPCRs has the potential to lead to significant breakthroughs in the treatment of cardiovascular and metabolic disorders.