Company Filing History:
Years Active: 2023-2024
Title: Innovations by Daniel Rodion Rathbone
Introduction
Daniel Rodion Rathbone is an accomplished inventor based in Somerville, MA. He has made significant contributions to the field of organ-on-chip technology, holding 2 patents that showcase his innovative approach to biomedical engineering.
Latest Patents
Rathbone's latest patents include advancements in organ-on-chip platforms with reduced fluid volumes. These platforms are designed to operate with circulating fluid volumes below 1000 μL, ideally around 500 μL or less. They are adjustable for culturing cells with varying oxygen demands at different seeding densities. Each platform features at least one lane that includes cell culture wells, oxygenators for fluid oxygenation, and a pump system with at least one pump per lane. The oxygenator is designed with a separate fluid path for oxygenating the fluid, which allows for precise control and measurement of oxygen concentration, thereby enhancing the efficiency of the system.
Another notable patent focuses on on-platform pumps that provide greater flexibility and design freedom for organ-on-chip platforms. Rathbone has developed electromagnetic (EM) pumps that utilize electrical energy, making them portable and efficient. The EM pump operates with a low energy consumption actuator, which employs a latching design that requires only a brief pulse of energy to switch states. This innovative design allows for the recovery of kinetic energy during the reverse stroke, further minimizing energy usage. Additionally, the platforms are designed for single-use with onboard diaphragm micro-pumps and various valve and pump geometries, ensuring reliable performance.
Career Highlights
Rathbone is affiliated with the Massachusetts Institute of Technology, where he continues to push the boundaries of organ-on-chip technology. His work has garnered attention for its potential applications in drug testing and disease modeling.
Collaborations
He collaborates with esteemed colleagues such as David L. Trumper and Brij Mohan Bhushan, contributing to a dynamic research environment that fosters innovation.
Conclusion
Daniel Rodion Rathbone's contributions to organ-on-chip technology exemplify the intersection of engineering and biology. His patents reflect a commitment to advancing biomedical research and improving healthcare solutions.