Location History:
- Brisbane, CA (US) (2020 - 2021)
- South San Francisco, CA (US) (2024)
Company Filing History:
Years Active: 2020-2024
Title: The Innovative Contributions of Daniel Marquess
Introduction
Daniel Marquess is a notable inventor based in Brisbane, California. He has made significant contributions to the field of ophthalmology through his innovative research and inventions. With a total of 3 patents, Marquess is recognized for his work in developing methods to address age-related eye conditions.
Latest Patents
One of Marquess's latest patents focuses on methods of inhibiting pathological angiogenesis. This invention is based on the discovery that many eye conditions associated with aging are mediated at least in part by cells bearing a senescent phenotype. Senescent cells accumulate with age and express factors that contribute to the pathophysiology of age-related conditions. The data show that in age-matched patients, the severity of age-related conditions correlates with the abundance of senescent cells. Clearing senescent cells can help abrogate these conditions. Marquess has developed small molecule drugs that remove senescent cells from affected tissue in the eye. These drugs have special efficacy in treating ophthalmic conditions. They not only inhibit the progression of the disease but can also reverse some of the pathophysiology, such as neovascularization and vaso-obliteration, that lead to vision loss. These senolytic agents have an appropriate dose and specificity profile to be effective in the clinical management of previously intractable ophthalmic conditions.
Career Highlights
Daniel Marquess is currently associated with Unity Biotechnology, Inc., where he continues to advance his research in the field of ophthalmology. His work has garnered attention for its potential to improve the quality of life for individuals suffering from age-related eye diseases.
Collaborations
Marquess collaborates with talented professionals in his field, including Pam Tsuruda and Jill Hopkins. Their combined expertise contributes to the innovative environment at Unity Biotechnology, Inc.
Conclusion
Daniel Marquess is a pioneering inventor whose work in ophthalmology has the potential to transform the treatment of age-related eye conditions. His innovative methods and dedication to research continue to make a significant impact in the field.