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For the Inventor, By the Inventor

Somerville, MA, United States of America

Daniel M Horowitz

USPTO Granted Patents = 14


Average Co-Inventor Count = 2.5

ph-index = 8

Forward Citations = 498(Granted Patents)


Location History:

  • Somerville, MA (US) (2000 - 2003)
  • Alexandria, VA (US) (2007 - 2014)

Company Filing History:

goldMedal14 out of 102 
 
Metabolix, Inc.
 patents

Years Active: 2000-2014

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14 patents (USPTO):Explore Patents
1. 8771720 - Medical device comprising polyhydroxyalkanoate having pyrogen removed using oxidizing agent (2014-07-08),
2. 8231889 - Method of forming medical devices having pyrogen removed for in vivo application (2012-07-31),
3. 7906135 - Medical device comprising polyhydroxyalkanoate having pyrogen removed (2011-03-15),
4. 7244442 - Method for making devices using polyhydroxyalkanoate having pyrogen removed (2007-07-17),
5. 6623749 - Medical device containing polyhydroxyalkanoate treated with oxidizing agent to remove endotoxin (2003-09-23),
6. 6605262 - Methods and apparatus for the production of amorphous polymer suspensions (2003-08-12),
7. 6429285 - Polymer compositions providing low residue levels and methods of use thereof (2002-08-06),
8. 6368836 - Method of decolorizing or deodorizing polyhydroxyalkanoates from biomass with ozone (2002-04-09),
9. 6340580 - Methods for purifying polyhydroxy alkanoates (2002-01-22),
10. 6323276 - Methods and apparatus for the production of amorphous polymer suspensions (2001-11-27),
11. 6245537 - Removing endotoxin with an oxdizing agent from polyhydroxyalkanoates produced by fermentation (2001-06-12),
12. 6228934 - Methods and apparatus for the production of amorphous polymer suspensions (2001-05-08),
13. 6214920 - Polyhydroxyalkanoate molding compositions (2001-04-10),
14. 6071998 - Polyhydroxyalkanoate molding compositions (2000-06-06),

Title: Innovations in Medical Devices by Daniel M. Horowitz

Introduction

Daniel M. Horowitz is a prominent inventor based in Somerville, MA (US), known for his significant contributions to the field of biomedical engineering. With a total of 14 patents to his name, he has focused on developing innovative medical devices that utilize polyhydroxyalkanoates (PHAs) for various applications.

Latest Patents

Horowitz's latest patents include groundbreaking work on medical devices comprising polyhydroxyalkanoate that has undergone depyrogenation using an oxidizing agent. These PHAs are chemically modified to enhance their physical and chemical properties, targeting biodegradability and clearance by the reticuloendothelial system (RES). His methods for depyrogenating PHA polymers, prepared through bacterial fermentation processes, ensure that pyrogens are removed without adversely affecting the polymers' inherent chemical structures and physical properties. The PHAs developed by Horowitz exhibit advantageous processing characteristics, such as low melting points and solubility in non-toxic solvents. These materials are suitable for in vivo applications, including tissue coatings, stents, sutures, tubing, bone prostheses, tissue regeneration devices, wound dressings, drug delivery systems, and diagnostic and prophylactic uses.

Career Highlights

Horowitz has made significant strides in the biomedical field through his work at Metabolix, Inc. His innovative approach to utilizing PHAs has positioned him as a leader in the development of sustainable and effective medical devices. His research has the potential to revolutionize various medical applications, improving patient outcomes and advancing the field of tissue engineering.

Collaborations

Throughout his career, Horowitz has collaborated with notable colleagues, including Tillman U. Gerngross and Simon F. Williams. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas in the pursuit of advancing medical technology.

Conclusion

Daniel M. Horowitz's contributions to the field of biomedical engineering through his innovative patents and collaborative efforts have made a significant impact on medical device development. His work continues to pave the way for advancements in healthcare and medical technology.

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