Daniel George Fordham

Title: Daniel George Fordham: Innovator in Nucleic Acid Detection

Introduction

Daniel George Fordham, an accomplished inventor based in Oxford, GB, has made significant contributions to the field of nucleic acid detection, holding a total of seven patents. His innovative techniques and methods demonstrate a remarkable understanding of molecular biology and engineering, paving the way for advancements in diagnostics and research.

Latest Patents

Fordham's latest patents include a novel method of determining the presence or absence of a target analyte through a combination of immobilization, specific binding, and detection using a transmembrane pore. This patent outlines a procedure that involves immobilizing any target analyte on a surface, utilizing a first detection agent, and incorporating a reporter polynucleotide to confirm the analyte's presence. The use of a transmembrane pore to detect the reporter polynucleotide provides an innovative approach for analyte identification.

Another recent patent focuses on nucleic acid detection by guiding through a nanopore. This technique involves the formation of a complex between a guide polynucleotide and a target polynucleotide, alongside a polynucleotide-guided effector protein. The method further employs a membrane with a transmembrane pore and requires monitoring interactions resulting from the complex to determine the presence of the target polynucleotide in the sample.

Career Highlights

Currently, Daniel Fordham is associated with Oxford Nanopore Technologies Limited, a company renowned for its advancements in portable DNA sequencing technology. His work there has enabled groundbreaking developments that enhance the capabilities of genetic analysis, making testing more accessible and efficient.

Collaborations

Fordham collaborates with esteemed colleagues James White and Daniel John Turner, contributing to a dynamic environment of creativity and scientific advancement. This collaboration fosters innovation and helps refine methods that are crucial in the field of nucleic acid detection.

Conclusion

Through his inventive work and collaborations, Daniel George Fordham continues to push the boundaries of what is possible in genetic detection and analysis. His patents not only illustrate his expertise but also promise significant implications for diagnostics in medicine and research, solidifying his reputation as a significant contributor to contemporary science.