Company Filing History:
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Years Active: 1995-1997
Title: Danae D Christodoulou: Innovator in Nitric Oxide Sensing Technology
Introduction
Danae D Christodoulou is a prominent inventor based in Frederick, MD (US). She has made significant contributions to the field of nitric oxide sensing technology, holding 2 patents that showcase her innovative approach to measurement techniques.
Latest Patents
One of her latest patents involves a nitric oxide sensor, which is an electrode sensor designed to specifically and quantitatively measure nitric oxide. This invention includes a method for preparing and utilizing the electrode sensor to measure nitric oxide concentration in various solutions. The microsensor is characterized by a thermally-sharpened carbon fiber with a tip diameter of about 0.5-0.7 µm, coated with multiple layers of p-type semiconducting polymeric porphyrin and cationic exchanger. It can operate in amperometric, voltammetric, or coulometric modes, demonstrating a linear response up to approximately 300 µM, a response time of better than 10 msec, and a detection limit of about 10 nM. This sensor effectively discriminates against nitrite, which is a common interferant in nitric oxide measurements. Additionally, she has developed mixed ligand metal complexes of nitric oxide-nucleophile adducts that are useful as cardiovascular agents.
Career Highlights
Danae has worked with notable organizations, including the United States of America as represented by the Department of Health and the University of North Carolina at Chapel Hill. Her work has significantly advanced the understanding and measurement of nitric oxide in various applications.
Collaborations
Throughout her career, Danae has collaborated with esteemed colleagues such as David A Wink and Tadeusz Malinski. These partnerships have contributed to the success and impact of her inventions.
Conclusion
Danae D Christodoulou is a trailblazer in the field of nitric oxide sensing technology. Her innovative patents and collaborations highlight her commitment to advancing scientific knowledge and practical applications in this important area.