Company Filing History:
Years Active: 2002-2004
Title: Damon A Harvey: Innovator in Genetic Engineering
Introduction
Damon A Harvey is a notable inventor based in Berkeley, CA (US). He has made significant contributions to the field of genetic engineering, holding a total of 3 patents. His work focuses on innovative methods for gene expression inhibition in eukaryotic cells.
Latest Patents
Harvey's latest patents include groundbreaking inventions related to the cytoplasmic inhibition of gene expression. The first patent provides novel genetic constructions for the expression of inhibitory RNA in the cytoplasm of eukaryotic cells. This inhibitory RNA can be an anti-sense RNA or a co-suppressor RNA, functioning to reduce the expression of a gene of interest in the target cell. The genetic constructions are capable of replicating in the cytoplasm of various eukaryotic cells, including plant cells, yeast cells, and mammalian cells. When targeting plant cells, the genetic construction is preferably derived from a plant RNA virus, utilizing subgenomic promoters from tobamoviruses in combination with the RNA encoding region. A preferred embodiment of this invention induces plant cells to produce elevated levels of the carotenoid phytoene by inhibiting the expression of the enzyme phytoene desaturase.
Another patent by Harvey focuses on cytoplasmic inhibition of gene expression by viral RNA, reiterating the innovative genetic constructions for inhibitory RNA in eukaryotic cells. This patent shares similar features with the previous one, emphasizing the potential for applications in various eukaryotic cell types.
Career Highlights
Damon A Harvey is associated with Large Scale Biology Corporation, where he continues to advance his research in genetic engineering. His work has contributed to the understanding and manipulation of gene expression, paving the way for future innovations in biotechnology.
Collaborations
Harvey has collaborated with notable colleagues, including Monto H Kumagai and Guy R Della-Cioppa, enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Damon A Harvey's contributions to genetic engineering through his innovative patents demonstrate his commitment to advancing the field. His work not only enhances our understanding of gene expression but also opens new avenues for biotechnological applications.