Dale G McLeod

Title: Dale G McLeod: Innovator in Pharmaceutical Prodrugs

Introduction

Dale G McLeod is a notable inventor based in Ledyard, CT (US). She has made significant contributions to the field of pharmaceuticals, particularly in the development of prodrugs aimed at treating bacterial infections. With a total of 4 patents to her name, her work has had a meaningful impact on medical science.

Latest Patents

Among her latest patents is the invention of Penem prodrugs, which are orally bioavailable prodrugs of sulopenem. This invention includes solvates and hydrates, along with methods for their preparation, formulation, and use in treating and preventing infections in mammals, including humans. Another significant patent is for a beta-lactamase inhibitor prodrug, which involves prodrugs of 6-β-hydroxymethylpenicillanic acid sulfone. This patent outlines pharmaceutical compositions that include a prodrug or its solvate, an optional beta-lactam antibiotic, and a pharmaceutically acceptable excipient. Furthermore, it describes methods for enhancing the therapeutic effectiveness of beta-lactam antibiotics in mammals.

Career Highlights

Dale G McLeod is currently associated with Pfizer Corporation, a leading global pharmaceutical company. Her work at Pfizer has allowed her to focus on innovative solutions in drug development, particularly in the area of antibiotic resistance.

Collaborations

Throughout her career, Dale has collaborated with notable colleagues, including Anthony Marfat and Simon Bailey. These collaborations have contributed to her success in the field of pharmaceutical research.

Conclusion

Dale G McLeod's contributions to the development of pharmaceutical prodrugs highlight her innovative spirit and dedication to improving healthcare. Her work continues to influence the treatment of bacterial infections, showcasing the importance of research and innovation in medicine.