Daisuke Mori

Title: Daisuke Mori: Innovator in Heparin Synthesis

Introduction

Daisuke Mori is a prominent inventor based in Rensselaer, NY (US). He has made significant contributions to the field of biochemistry, particularly in the synthesis of heparin. With a total of three patents to his name, Mori's work focuses on developing alternatives to traditional heparin sources.

Latest Patents

Mori's latest patents include innovative methods for synthesizing biosynthetic heparin. This process aims to create a bioequivalent to porcine USP Heparin Sodium, utilizing three intermediates that start from heparosan. Another notable patent involves the enzymatic preparation of increased anticoagulant bovine-sourced heparin. This method enhances the anticoagulant activity of heparin by modifying its structure through the addition of sulfuryl groups, resulting in a product that closely resembles porcine intestinal heparin. The modified heparin demonstrates significant anti-FXa and anti-FIIa activities, meeting U.S. Pharmacopeia specifications.

Career Highlights

Daisuke Mori is affiliated with Rensselaer Polytechnic Institute, where he conducts his research and development. His work has garnered attention for its potential to provide viable alternatives to existing heparin sources, which are critical in medical applications.

Collaborations

Mori collaborates with notable colleagues, including Makoto Hirakane and Li Fu, who contribute to his research endeavors.

Conclusion

Daisuke Mori's innovative work in heparin synthesis showcases his commitment to advancing biochemistry and providing alternatives to traditional medical treatments. His contributions are paving the way for future developments in anticoagulant therapies.