D Y Gao

Title: Innovations in Cryobiology: The Contributions of D Y Gao

Introduction

D Y Gao is a prominent inventor based in Indianapolis, IN (US), known for her significant contributions to the field of cryobiology. With a total of three patents to her name, she has developed innovative methods and devices that optimize the protocols for the addition and removal of cryoprotectants in biological cells. Her work is crucial for advancing the preservation of biological materials.

Latest Patents

D Y Gao's latest patents include groundbreaking technologies that focus on cell-type specific methods and devices for low-temperature applications. One of her notable patents describes a mathematical model that utilizes four equations to predict optimal protocols for adding or removing cryoprotectants from biological cells. This model requires experimentally found data specific to cell type and species, particularly regarding the osmotic tolerance of the cells. The equations also necessitate the cryoprotectant permeability coefficient and the water permeability coefficient of the cells' plasma membrane. These coefficients are determined through experimental data on the kinetic volume change of the cell type in response to known concentrations and temperatures of cryoprotectants. Additionally, her patents disclose preferred methods and devices for efficiently managing cryoprotectant levels in animal cells.

Career Highlights

D Y Gao is currently employed at Methodist Hospital of Indiana, Inc., where she continues to push the boundaries of cryobiological research. Her innovative work has garnered attention in the scientific community, contributing to advancements in the preservation of biological materials and enhancing the understanding of cellular responses to cryoprotectants.

Collaborations

Throughout her career, D Y Gao has collaborated with esteemed colleagues, including John K Critser and Robert J Demeter. These partnerships have facilitated the exchange of ideas and expertise, further enriching her research and contributions to the field.

Conclusion

D Y Gao's innovative work in cryobiology exemplifies the importance of research in optimizing biological preservation techniques. Her patents and collaborations highlight her commitment to advancing scientific knowledge and improving methodologies in the field.