D Thomas Rutkowski

Title: D Thomas Rutkowski: Innovator in Protein Regulation

Introduction

D Thomas Rutkowski is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of protein regulation, holding 2 patents that focus on innovative methods and compositions for identifying novel protein conformers.

Latest Patents

Rutkowski's latest patents revolve around the theme of conformational and topological protein regulation. These patents provide methods for identifying novel conformers of proteins that were previously unknown. By utilizing chimeric genes that replace a native signal sequence with a different one, Rutkowski's work allows for the production of conformers. This enables a comparison between the native protein and the product of the chimeric gene. When differences in conformation are observed, the resulting proteins can be used for various applications, including the production of antibodies, elucidating mechanisms associated with both native and different conformer proteins, and conducting assays for the presence of these conformers in physiological samples. Furthermore, if the formation of a conformer is linked to a diseased state, it can be employed in screens to identify potential drug candidates.

Career Highlights

Rutkowski is affiliated with the University of California, where he continues to advance research in protein regulation. His work has garnered attention for its potential applications in drug discovery and therapeutic development.

Collaborations

Some of his notable coworkers include Vishwanath R Lingappa and Ramanujan S Hegde, who contribute to the collaborative research environment at the University of California.

Conclusion

D Thomas Rutkowski's innovative work in protein regulation exemplifies the impact of scientific research on drug discovery and therapeutic advancements. His contributions continue to shape the understanding of protein conformations and their implications in health and disease.