This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignee: Elan Pharmaceuticals, Inc.. Active years: 2009-2010.
Company Filing History:
Years Active: 2009-2010
Title: D Bryan Prince: Innovator in Alzheimer's Research
Introduction
D Bryan Prince is a notable inventor based in Parchment, MI (US). He has made significant contributions to the field of biochemistry, particularly in the study of human beta secretase, an enzyme implicated in Alzheimer's disease. With a total of 2 patents, his work is paving the way for advancements in therapeutic interventions.
Latest Patents
D Bryan Prince's latest patents include a method for crystallizing human beta secretase in complex with an inhibitor. This patent describes an inhibitor-bound form of human beta secretase, also known as memapsin 2 and BACE, particularly in a glycosylated form as expressed in Chinese hamster ovary (CHO), HEK293 cells, or in insect cells as part of a Baculovirus expression system. The crystallization process has led to the resolution of the three-dimensional x-ray crystal structure to 3.2 Å, which is instrumental in solving the structure of other molecules or molecular complexes and in designing inhibitors of human beta secretase activity. Another patent focuses on the crystallization and structure determination of glycosylated human beta secretase, further emphasizing its relevance in Alzheimer's research.
Career Highlights
D Bryan Prince is currently associated with Elan Pharmaceuticals, Inc., where he continues to contribute to innovative research in the field. His work has been pivotal in understanding the molecular mechanisms of Alzheimer's disease, which has far-reaching implications for treatment strategies.
Collaborations
Some of his notable coworkers include Jim D Durbin and Timothy Earl Benson. Their collaborative efforts have enhanced the research output and innovation at Elan Pharmaceuticals.
Conclusion
D Bryan Prince's contributions to the field of biochemistry and Alzheimer's research are commendable. His innovative patents and collaborative work are setting the stage for future advancements in therapeutic solutions.