Company Filing History:
Years Active: 2015
Title: Inventor Céline Gales: Innovating Biosensors in Toulouse
Introduction: Céline Gales is an accomplished inventor based in Toulouse, France, recognized for his contributions to the field of biosensors. With a focus on monitoring receptor-mediated G-protein activation, Gales has developed innovative technologies that significantly enhance our understanding of biological processes.
Latest Patents: Céline Gales holds one patent titled "Biosensors for monitoring receptor-mediated G-protein activation." This invention revolves around novel biosensors utilizing bioluminescence resonance energy transfer (BRET). These biosensors are capable of monitoring rapid interactions and conformational changes within G protein-coupled receptor (GPCR)/G protein complexes, ultimately reflecting the activation status of the receptor. They serve as highly sensitive and quantitative assays for identifying various ligands targeting GPCRs, including agonists, antagonists, inverse agonists, and partial agonists. Additionally, Gales' biosensors allow for multiplexing within receptor/G protein complexes, enabling the mapping of ligand textures and facilitating the real-time examination of interactions in living cells.
Career Highlights: Céline Gales has made significant strides in the biotechnological landscape, bolstered by his affiliation with Université de Montréal. His work has not only advanced the scientific community's knowledge of GPCR function but has also opened new avenues for therapeutic discovery.
Collaborations: Throughout his career, Gales has collaborated with notable scientists, including Michel Bouvier and Billy Breton. These collaborations have fostered an environment of innovation and have been pivotal in the development of cutting-edge biosensing technologies.
Conclusion: Céline Gales continues to make impactful contributions to the field of biosensors, leveraging his expertise to advance our understanding of receptor dynamics. His work at Université de Montréal positions him as a key figure in biotechnological research, with the potential to influence future innovations in drug discovery and therapeutic applications.