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Years Active: 2016
Title: Cynthia Timmers: Innovator in Cancer Diagnosis and Treatment
Introduction
Cynthia Timmers is a prominent inventor based in Columbus, OH (US). She has made significant contributions to the field of cancer research, particularly in the diagnosis and treatment of cancer susceptibilities and defective DNA repair mechanisms. Her innovative work has led to the development of methods and compositions that are crucial for advancing cancer diagnostics.
Latest Patents
Cynthia Timmers holds a patent for "Methods and compositions for the diagnosis of cancer susceptibilities and defective DNA repair mechanisms and treatment thereof." This patent provides methods and compositions for diagnosing cancer susceptibilities and defective DNA repair mechanisms. Among the sequences provided, the FANCD2 gene has been identified, along with probes and primers for screening patients in genetic-based tests. This work is essential for diagnosing Fanconi Anemia and cancer. The FANCD2 gene can also be targeted in vivo for preparing experimental mouse models to screen new therapeutic agents for treating conditions involving defective DNA repair. The FANCD2 polypeptide has been sequenced and exists in two isoforms, identified as FANCD2-S and the monoubiquinated FANCD-L form. Antibodies, including polyclonal and monoclonal antibodies, have been prepared to distinguish these isoforms and have been utilized in diagnostic tests to determine whether a subject has an intact Fanconi Anemia/BRCA pathway.
Career Highlights
Throughout her career, Cynthia has worked with esteemed institutions such as the Dana-Farber Cancer Institute and Oregon Health & Science University. Her research has significantly impacted the understanding of cancer genetics and treatment options.
Collaborations
Cynthia has collaborated with notable scientists, including Alan D. D'Andrea and Toshiyasu Taniguchi. These collaborations have furthered her research and contributed to advancements in cancer diagnostics and therapies.
Conclusion
Cynthia Timmers is a trailblazer in the field of cancer research, with her innovative patent and collaborations paving the way for future advancements in cancer diagnosis and treatment. Her work continues to inspire and influence the scientific community.