Cylia Rochat

Title: The Innovative Contributions of Cylia Rochat

Introduction

Cylia Rochat is a prominent inventor based in Lausanne, Switzerland. She has made significant contributions to the field of biotechnology, particularly in the development of innovative solutions for treating motoneuron diseases. With a total of 2 patents, her work is paving the way for advancements in RNA interference technologies.

Latest Patents

One of her latest patents is a bicistronic AAV vector for RNA interference in ALS. This invention relates to a bicistronic expression vector designed to silence a gene specifically in astrocytes and neurons. It comprises two expression cassettes, each containing a first and a second silencer sequence. The expression of the first silencer sequence within astrocytes is regulated by an astrocyte-specific promoter, while the second silencer sequence within neurons is regulated by a neuron-specific promoter. In a preferred embodiment, both silencer sequences are SOD1 silencer sequences. The patent also describes a pharmaceutical composition that includes this bicistronic vector and its use in treating motoneuron diseases.

Career Highlights

Cylia has worked at esteemed institutions such as École Polytechnique Fédérale de Lausanne. Her research and innovations have garnered attention in the scientific community, contributing to the advancement of therapeutic strategies for neurodegenerative diseases.

Collaborations

Throughout her career, Cylia has collaborated with notable colleagues, including Julianne Aebischer and Bernard Schneider. These partnerships have enhanced her research efforts and expanded the impact of her inventions.

Conclusion

Cylia Rochat's innovative work in biotechnology, particularly her patents related to RNA interference, showcases her commitment to advancing medical science. Her contributions are vital in the ongoing fight against motoneuron diseases, and her collaborations further amplify the significance of her research.