Curtis J Layton

Title: Innovations of Curtis J Layton in Protein Display Technology

Introduction

Curtis J Layton is a notable inventor based in Redwood City, CA, who has made significant contributions to the field of biotechnology. He holds three patents that focus on innovative methods for displaying proteins and peptides on DNA. His work has the potential to revolutionize various applications in genetic and pharmacological research.

Latest Patents

Layton's latest patents include groundbreaking devices and methods for the display of encoded peptides, polypeptides, and proteins on DNA. One of his notable inventions describes a novel method in which individual proteins or peptides remain associated with the DNA encoding them. This method allows proteins or peptides to be generated by in vitro translation of DNA templates, either free in solution or arrayed on a solid support, ensuring that they remain immobilized on their DNA templates. High throughput sequencing can be combined with high throughput functional characterization of encoded proteins and peptides, allowing for the identity of each protein or peptide to be determined by DNA sequencing. Functional studies can then be carried out directly on each protein or peptide while it is immobilized on the DNA template encoding it. The methods developed by Layton are expected to find numerous applications, including high throughput genetic or pharmacological screening, epitope mapping, and protein engineering and directed evolution.

Career Highlights

Curtis J Layton is affiliated with Leland Stanford Junior University, where he continues to advance his research in protein display technology. His innovative approaches have garnered attention in the scientific community, contributing to the understanding of protein interactions and functionalities.

Collaborations

Layton collaborates with William J Greenleaf, further enhancing the research and development of his patented technologies.

Conclusion

Curtis J Layton's work in the field of protein display technology represents a significant advancement in biotechnology. His innovative methods have the potential to impact various areas of research and application, paving the way for future discoveries.