Company Filing History:
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1 out of 832,912 Years Active: 2019
Title: Corrado Spadafora: Innovator in Pharmaceutical Research
Introduction
Corrado Spadafora is a notable inventor based in Rome, Italy. He has made significant contributions to the field of pharmaceutical research, particularly in the development of compounds that target cellular processes related to cancer and other pathologies. With a total of 2 patents, his work has the potential to impact therapeutic strategies in oncology.
Latest Patents
Spadafora's latest patents include innovative approaches to combat cellular proliferation and differentiation. One of his key inventions is titled "Non-nucleosidic inhibitors of reverse transcriptase as antagonists of cell proliferation and inducers of cell differentiation." This invention focuses on the use of Reverse Transcriptase (RT) inhibitor compounds to prepare pharmaceutical compositions aimed at counteracting the loss of cellular differentiation in both tumor and non-tumor pathologies. The compounds, such as nevirapine, efavirenz, and delavirdine, are particularly effective as they bind to the hydrophobic pocket on the RT subunit p66.
Another significant patent is "Monoclonal antibody to human line-1 ORF2 protein and method for early detection of transforming cells in pre-neoplastic tissues of a human subject." This patent describes a monoclonal antibody that specifically binds to the human Long Interspersed Element-1 ORF2 encoded protein (L1-ORF2p). It provides methods for early detection of cell transformation in pre-neoplastic tissues, which can be crucial for predicting cancer patient responses to NNRTI treatments.
Career Highlights
Throughout his career, Corrado Spadafora has worked with various research institutions, including the Istituto Superiore Di Sanita. His research has focused on developing innovative solutions to complex medical challenges, particularly in the realm of cancer treatment.
Collaborations
Spadafora has collaborated with notable colleagues such as Ilaria Sciamanna and Chiara De Luca. These partnerships have contributed to the advancement of his research and the successful development of his patented inventions.
Conclusion
Corrado Spadafora's contributions to pharmaceutical research through his patents highlight his innovative approach to addressing critical health issues. His work continues to pave the way for advancements in cancer treatment and early detection methods.