Cornelia Kruse-Mueller

Title: The Innovative Journey of Cornelia Kruse-Mueller

Introduction

Cornelia Kruse-Mueller, based in Edewecht, Germany, is a distinguished inventor recognized for her contributions to the field of nucleic acid detection and immobilization. With a total of three patents to her name, she stands out as a leading figure in biotechnological innovations.

Latest Patents

Kruse-Mueller's latest inventions focus on methods that enhance the detection and handling of nucleic acids. One of her significant patents is a method of detecting nucleic acids, which involves converting nucleic acids into single-stranded forms under alkaline conditions. This method utilizes at least one detergent from anionic, non-ionic, or zwitterionic categories to facilitate the process. The approach includes adding an immobilizable or immobilized capture probe that hybridizes with the nucleic acid, ultimately allowing for the detection of synthesized, immobilized hybrids.

Additionally, she has developed a method for electrochemiluminescent labeling of nucleic acids, designed for immobilizing nucleic acids through hybridization with a capture probe that is protected against enzymatic extension and degradation. This innovation reflects her commitment to advancing methodologies in molecular biology.

Career Highlights

Throughout her career, Cornelia Kruse-Mueller has made significant contributions to renowned organizations such as Roche Diagnostics GmbH and Boehringer Mannheim GmbH. Her experiences in these prestigious companies have undoubtedly shaped her innovative spirit and technical expertise, allowing her to explore novel solutions in her field.

Collaborations

Collaboration plays a vital role in advancing scientific research, and Kruse-Mueller has worked alongside notable colleagues, including Sibylle Berner and Cortina Kaletta. These partnerships have facilitated knowledge sharing and have been crucial in the development of her patented technologies.

Conclusion

Cornelia Kruse-Mueller exemplifies the impact that dedicated inventors can have in the realm of biotechnology. Her innovative methods for nucleic acid detection and immobilization pave the way for significant advancements in molecular biology and diagnostics. As she continues her work, her contributions will undoubtedly inspire future inventors and researchers in this crucial field.