Roche Diagnostics Gmbh

Boehringer Mannheim Gmbh

Cornelia Kruse-Mueller

Sibylle Berner

Cortina Kaletta

Stefanie Koehler

Method of detecting a nucleic acid by converting the nucleic acid into a single-stranded nucleic acid under alkaline conditions, wherein at least one detergent from the group of anionic, non-ionic and zwitterionic detergents is present, adding an immobilizable or immobilized capture probe, hybridizing the capture probe with the nucleic acid under immobilization of the nucleic acid via the capture probe and detecting the amount of synthesized, immobilized hybrid.

Method of detecting nucleic acids

Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.

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Edewecht, Germany

Cornelia Kruse-Mueller