Location History:
- Pierrefonds, CA (1997 - 1999)
- Quebec, CA (1999)
Company Filing History:
Years Active: 1997-1999
Title: Innovations in Wound Healing: The Contributions of Clark Bennett
Introduction
Clark Bennett, an accomplished inventor based in Pierrefonds, CA, has made significant advancements in the field of wound healing through his innovative patents. With a total of three patents to his name, his work focuses on utilizing glycosaminoglycans and their degrading enzymes to manipulate cellular interactions and enhance healing processes.
Latest Patents
Bennett's latest patent introduces a groundbreaking approach to wound healing by employing glycosaminoglycans, including heparinases 1, 2, and 3, as well as chondroitinases AC and B derived from the Gram-negative bacteria Flavobacterium heparinum. His invention outlines how these enzymes can be used separately or in combination to influence cell proliferation effectively. By administering heparinases, the degradation of heparan sulfate components within the extracellular matrix is achieved, facilitating the migration of heparin-binding growth factors stored in the matrix to adjacent cells. This mechanism enhances tissue dynamics by increasing the mobility of chemoattractant agents and growth factors, thereby promoting faster wound healing.
Additionally, the patent details methods for selectively removing chondroitin sulfates from cell surfaces, which increases the availability of growth factor receptors. Conversely, the targeted removal of heparan sulfate inhibits cell proliferation by downregulating the cell’s response to growth factors. The invention also includes innovative techniques for expressing heparinases and a multi-step protein purification method.
Career Highlights
Clark Bennett has had a notable career, working at leading companies in the biotechnology sector, including Ibex Technologies Ltd. and Ibex Technologies R&D, Inc. His contributions have greatly impacted the field of enzyme technology and tissue healing.
Collaborations
Throughout his career, Bennett has collaborated with esteemed colleagues such as Joseph J. Zimmermann and Hongsheng Su. These partnerships have allowed him to expand the reach of his innovations and enhance the science behind wound healing solutions.
Conclusion
Clark Bennett's inventive approach to wound healing marks a significant step forward in biotechnology. His patents not only provide new methods for improving cellular interaction and proliferation but also pave the way for future research in the field. With a strong foundation built on collaboration and innovation, Bennett continues to make a lasting impact on healthcare and treatment methodologies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.