This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: University of Pennsylvania, Other. Active years: 2003-2014.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 2,659 
1 out of 834,513 Years Active: 2003-2014
Title: Innovations by Claire Mitchell in Ophthalmology
Introduction
Claire Mitchell is an accomplished inventor based in Philadelphia, PA (US). She has made significant contributions to the field of ophthalmology, particularly in the treatment of age-related macular degeneration and intraocular pressure management. With a total of two patents to her name, her work is paving the way for new therapeutic approaches.
Latest Patents
One of Claire's latest patents is a method for the treatment of macular degeneration by modulating P2Y12 or P2X7 receptors. This innovative method aims to treat or prevent age-related macular degeneration (AMD) by restoring normal lysosomal pH in retinal pigment epithelium (RPE) cells. By modulating the action of the P2X7 and/or P2Y12 receptors, the method decreases the acidity of RPE lysosomes, thereby preventing the accumulation of harmful waste products. Additionally, she has developed methods for selecting and quantifying the effectiveness of drugs to restore pH and determine outer segment clearance rates using a high-throughput screening protocol.
Another significant patent involves methods for reducing intraocular pressure using A3 adenosine receptor antagonists. This invention focuses on decreasing intraocular pressure through the administration of an A3 subtype adenosine receptor antagonist, a calmodulin antagonist, or an antiestrogen such as tamoxifen. These advancements are crucial for patients suffering from conditions that lead to elevated intraocular pressure.
Career Highlights
Claire has worked with prestigious institutions, including the University of Pennsylvania, where she has contributed her expertise in research and development. Her innovative approaches have garnered attention in the medical community, highlighting her role as a leading inventor in her field.
Collaborations
Throughout her career, Claire has collaborated with notable professionals, including Mortimer M Civan and Richard A Stone. These partnerships have further enhanced her research and development efforts, leading to impactful innovations.
Conclusion
Claire Mitchell's contributions to ophthalmology through her patents demonstrate her commitment to advancing medical science. Her innovative methods for treating macular degeneration and managing intraocular pressure are significant steps forward in improving patient care.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile